Which type of endoplasmic reticulum is involved in synthesizing fats and detoxifying drugs?

The smooth endoplasmic reticulum is primarily responsible for synthesizing lipids, including fats and phospholipids, which are essential components of cellular membranes. Additionally, it plays a crucial role in detoxifying various metabolic byproducts and drugs, particularly in liver cells, where it helps to modify and eliminate potentially harmful substances. Unlike the rough endoplasmic reticulum, which is studded with ribosomes and focuses on the synthesis of proteins, the smooth endoplasmic reticulum does not have ribosomes attached to its surface, highlighting its specialization in lipid synthesis and detoxification processes. Its structure allows for an extensive network of tubules that can accommodate these functions efficiently. The specific roles of the other types of endoplasmic reticulum, such as the rough and hypothetical forms mentioned, do not pertain to fat synthesis and detoxification abilities.